The Sweden captain has been absent after suffering a toe problem.
After missing the first part of our pre-season campaign, he did play on the US tour but was withdrawn at half-time of the game against Liverpool in South Carolina.
The centre-back made 28 appearances in all competitions for the Reds last term, scoring the winner in the home game against Luton Town.
Erik ten Hag will be buoyed by the reliable defender's potential return with the fixtures starting to come thick and fast, at home and abroad, for United.