Casemiro's second-half brace and a further effort from his compatriot Fred earned the Reds the win, with Andy Carroll being dismissed for the visitors after getting a second yellow card midway through the second period.
Reading substitute Amadou Mbengue headed home for the Royals to make it 3-1, but it is the Reds who are in the hat for Monday’s draw.
After an action-packed clash with flashpoints, superb goals, and VAR intervention, here are the key details you may have missed during our match against Reading…
DEALING WITH THE PHYSICAL THREAT
When Andy Carroll and Lucas Joao were named in the Reading attack, it became apparent that Harry Maguire and Victor Lindelof would have their work cut out against the Royals.