The Reds will play at Stadion Koln once again – the site of our 1-0 quarter-final victory over FC Copenhagen, after extra-time, on Monday evening – and, as in the last round, the tie will be contested over just one leg, due to the restructured format.
We last reached this stage of the Europa League in 2017, where we faced another Spanish side, Celta Vigo. United triumphed 2-1 on aggregate thanks to a Marcus Rashford free-kick in Vigo and a Marouane Fellaini header at Old Trafford.
Sevilla, meanwhile, are perennial fixtures at this stage of the competition.