The Reds won 5-2 as Casemiro and Bruno Fernandes both bagged doubles and Alejandro Garnacho also found the net.
It was an enjoyable occasion at Old Trafford and van Nistelrooy clearly relished a night to remember but admitted clearer chances were created, and missed, during the latter part of Erik ten Hag's reign.
Speaking to the official broadcasters, here are some of his comments...
SUPERB SUPPORT
"In the days leading up to this, it was with mixed feelings. Of course, I was sad to see Erik [ten Hag] go. He was the one that got me here.