The boss made six changes to his XI, on the back of a 4-0 win over Everton at the weekend, as the Reds were beaten 2-0 at Arsenal.
He is unwilling to take unnecessary risks with his players so Tyrell Malacia, Harry Maguire, Leny Yoro and Mason Mount are being treated particularly carefully.
Malacia was withdrawn at half-time in his first Premier League appearance since the victory over Fulham, in May 2023.
Maguire came off for Yoro, who made his competitive debut for he club, while Mount was substituted in the second half.
"It's not just because we like to change all the time," Amorim said of his selection.