The Reds pulled off an incredible second half last Thursday as we secured an impressive 6-2 advantage going into tonight's second leg at the Stadio Olimpico.
With a four-goal lead ahead of the return leg in the Europa League semi-final, Ole Gunnar Solskjaer has opted to alter his team slightly.
Eric Bailly, Mason Greenwood, Donny van de Beek are starting in Rome, with Victor Lindelof, Scott McTominay and Marcus Rashford moving to the bench.
LINE-UPS
United: De Gea; Wan-Bissaka, Bailly, Maguire (c), Shaw; Fred, van de Beek; Greenwood, Fernandes, Pogba; Cavani.