The Reds did take the lead inside the opening three minutes through Jesse Lingard, but the hosts immediately responded through the head of Charlie Austin, before going on to score three more times in the second-half courtesy of Lyndon Dykes (2) and Moses Odubajo.
Anthony Elanga reduced the deficit in the closing stages of a lively contest with the game's sixth goal, but it was the home side who ultimately claimed the spoils at full-time, at the Kiyan Prince Foundation Stadium.
FIRST HALF - LEVEL AT THE BREAK
Another week of pre-season preparations looked to have paid dividends inside the opening three minutes as United got off to a lightning-quick start.