United shot into a two-nil lead before the break thanks to goals from Harry Maguire and Bruno Fernandes, but Leeds responded in the second half.
Quickfire goals from both Rodrigo and Raphinha had pulled Marcelo Bielsa's side level before Fred and Elanga ensured all three points returned to M16.
FIRST HALF - UNITED GO TWO UP
It was the hosts who carved open the first real chance of the game after just five minutes, as Mateusz Klich cleverly found Jack Harrison unmarked with a lofted through pass. The Whites’ no.22 failed to trouble David De Gea however, firing his effort wide of the mark.