The Manchester United forward sustained a knock during the 3-1 victory over Fulham in the Emirates FA Cup quarter-final at Old Trafford on Sunday.
Our no.10 required treatment after being hurt in the build-up to Aleksandar Mitrovic's opener for the visitors and was later withdrawn in the 83rd minute, with Fred taking his place.
Marcus scored his 30th goal for club and country this season when bagging a brilliant winner in the 1-0 Europa League second-leg victory at Real Betis on Thursday night.
He netted three times for England at the World Cup finals, taking his international tally to 15 in 51 caps.