With the Reds already through to the last 16 as group winners, the German has opted to rotate the squad and assess players who did not feature in his first game as boss - the Premier League win over Crystal Palace at the weekend.
United line up as follows:
Henderson
Wan-Bissaka
Bailly
Matic (c)
Shaw
Van de Beek
Mata
Amad
Lingard
Greenwood
Elanga
Subs: Heaton, Kovar, Hardley, Mengi, Savage, Iqbal, Shoretire.
Read our pitchside interview with Rangnick below...
Ralf, it looks like an attacking side.