The Spanish champions were backed by vociferous support at the Wanda Metropolitano in the first leg but, although leading through Joao Felix's excellent header, they were undone by Anthony Elanga's late leveller.
With Atleti known for their high-octane approach under Diego Simeone, it is clear the Reds will need to match the energy and aggression provided by the opposition. To help in that respect, the Old Trafford faithful clearly has a major part to play if we are all to experience another special occasion under the lights.
In his exclusive pre-match chat with club media, the boss was in no doubt of what is required if United are to pull off a victory that would take us into Friday's draw for the quarter-finals.