The club legends will appear on our live broadcast from 19:10 BST and, in preparation, they have studied the state of play for their United Predictions.
Both are confident Erik ten Hag’s Reds will earn a 2-1 win at Stamford Bridge, and with Alejandro Garnacho playing a crucial role, but they can't agree on the XI.
Take a look at their respective picks before playing United Predictions...
SAMMY MCILROY’S PREDICTIONS
The Northern Ireland hero expects Harry Maguire to replace the injured Victor Lindelof at centre-back, and Casemiro to start again following a substitute appearance at the weekend.