Marc Skinner's side will be looking to make a positive first impression in our opening game of the primary European competition, and build on an unbeaten start to the new WSL season.
Our round-two opponents also come into this week's first leg in good form, having won two of their opening three domestic games in Division 1 Feminine.
Keep reading to find out everything you need to know ahead of a historic European night at LSV...
HOW YOU CAN FOLLOW THE GAME
Our first-leg meeting with the French side at Leigh Sports Village is scheduled to kick off at 20:00 BST.