The Reds will play in South Carolina for the very first time, taking Arne Slot's team on at Williams-Brice Stadium before a huge crowd.
United beat Real Betis 3-2 in San Diego on Wednesday, following a narrow 2-1 defeat to Arsenal in Los Angeles last weekend, and now aim to finish our jaunt to the USA on a high.
The match against our arch-rivals kicks off at 19:45 on Saturday, local time, which is 00:45 on Sunday morning for supporters in the United Kingdom.
Whether you are going to watch live, or plan to get up to speed later on Sunday, MUTV can hook you up.