We play high-flying Nottingham Forest - a team who have occupied one of the Champions League spots since December, when they beat us 3-2 at Old Trafford.
Facing Nuno Espirito Santo's well-organised defence and quicksilver attack won't be easy, but Ruben Amorim's men will have grown in confidence after knocking Real Sociedad out of Europe and beating Leicester City prior to the recent hiatus.
Here's what you need to know before our Premier League campaign resumes...
HOW TO WATCH AND FOLLOW
The match kicks off at 20:00 BST and is being shown live on TNT Sports in the UK.