The Reds are flying to Italy for a first-ever outing at the Gewiss Stadium, buoyed by the 3-0 victory at Tottenham on Saturday.
Ole's men are looking to consolidate top spot in Group F, following back-to-back home wins against Villarreal and Atalanta in the competition, with Tuesday night's 20:00 GMT kick-off preceding the weekend derby with Manchester City in the Premier League.
Paul Pogba is available despite his domestic ban, following the red card against Liverpool, and is a contender for a place in the line-up, while his fellow Frenchman, Anthony Martial, has been absent since the last international break.