David De Gea retains his place in goal after keeping a clean sheet in his 45-minute outing against Spurs and captains the side.
As against Spurs, Ole changes three of his back four with recent recruit Aaron Wan-Bissaka again the only player to retain his place at right-back.
Out go Chris Smalling, Marcos Rojo and Ashley Young, with Phil Jones, Victor Lindelof and Luke Shaw coming in.
Nemanja Matic starts alongside Scott McTominay, with Andreas Pereira, Paul Pogba and Mason Greenwood moving to the bench.
A 4-2-3-1 formation looks set to feature Daniel James, who makes his fifth start of Tour 2019, Jesse Lingard and Anthony Martial - scorer of United’s opener against Tottenham - support lone striker, Marcus Rashford, although the latter two could easily trade berths.