The Old Trafford clash with Graham Potter's Hammers was initially scheduled to be a 15:00 BST kick-off on Saturday 10 May, but has now been moved back as a result of our progression to the UEFA Europa League semi-finals.
It will now get under way just under 24 hours later, at 14:15 BST on Sunday 11 May. Tickets are available to buy here.
The alteration is a necessary one after United beat Lyon 7-6 on aggregate in our Europa League quarter-final tie, which culminated with that thrilling 5-4 victory in the second leg on Thursday night.