Two goals in five first-half minutes put the Reds in control after Ella Toone broke the deadlock before the half-hour mark, before Mollie Green notched up her 13th goal of the season six minutes later with a great turn and finish. Charlie Devlin then sealed the game with a delightful chip of the keeper with three minutes to spare.
Casey Stoney made four changes from Wednesday’s 7-0 away victory over Leicester City with Martha Harris, Aimee Palmer, Charlie Devlin and Lizzie Arnot coming into the fold.
The Reds, who beat Brighton & Hove Albion in the previous round, were up against a London Bees side which had appointed Rachel Yankey, a former team mate of Stoney, the day before.