A Dean Huijsen header gave the Cherries a first-half lead, which was added to by Justin Kluivert’s penalty and Antoine Semenyo’s finish in a three-minute spell during the second period.
With the quick turnaround in mind, Ruben Amorim shuffled his pack again following Thursday night’s Carabao Cup quarter-final defeat at Tottenham by making six changes as Andre Onana, Harry Maguire, Tyrell Malacia, Kobbie Mainoo, Amad and Joshua Zirkzee were restored to the line-up.
Andoni Iraola’s Bournemouth arrived in M16 having won their previous two away games. The visitors made just one change from their 1-1 draw at home to West Ham United on Monday night as Tyler Adams came into midfield for Lewis Cook, who dropped to the bench.