Ole Gunnar Solskjaer’s side start the European campaign with a trip to face the Swiss champions in Bern as Group F kicks off.
This is only the second time United and Young Boys are in the same Champions League group. Last time, in 2018, the Reds won home and away against the team in yellow-and-black kits.
Cristiano Ronaldo famously made his Premier League return with a brace against Newcastle United and the five-time Champions League winner could make his European return for United on Tuesday evening.
Here’s everything you need to know as we start our European journey once again…
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