After back-to-back 1-1 draws - away to Brighton and when hosting Arsenal - Marc Skinner's side seek a return to winning ways, coming up against a Villa side who have struggled so far, taking just two points from their opening six Barclays Women’s Super League matches.
Scroll down for more information you need to know ahead of the game…
HOW CAN I WATCH THE GAME?
All United fans can purchase tickets for the 18:45 GMT kick-off at Leigh Sports Village by going to tickets.manutd.com.
Alternatively, supporters who cannot attend can watch the action live on Sky Sports in the UK.