The Spanish side are ready for one of the biggest games in their history as they travel to Old Trafford in what is their first-ever European campaign.
Granada have beaten big sides to get to this stage but will need their most remarkable victory yet to come from behind against an in-form United side.
Ahead of the second leg of this quarter-final clash, here's everything you need to know about the match and Los Nazaries...
HOW CAN I FOLLOW THE GAME?
UK-based supporters can watch the match live on BT Sport 2 and BT Sport Ultimate.