Marc Skinner’s Reds will have the opportunity to make it two wins from two in this season’s competition during the 19:00 GMT kick-off, which will be played at Walton Hall Park in Merseyside.
Ahead of our trip across the north west, here is everything you need to know, starting with the live coverage info…
HOW CAN I WATCH THE GAME?
MUTV will be on air from 18:55 GMT, five minutes before kick-off, to bring you live and exclusive coverage of the Group A tie, which will also be viewable via ManUtd.