Manchester City’s medical team are assessing Kyle Walker after the defender sustained a foot problem ahead of Saturday's derby.
Walker limped out of Wednesday’s 4-1 win over Club Bruges towards the end of the second half.
Pep Guardiola confirmed that the 31-year-old suffered ‘a kick on his foot’, with City now ascertaining whether he will be available to face Manchester United.
City would likely switch Joao Cancelo to the right-hand side and call on Oleksandr Zinchenko at left back if the England international does not prove his fitness for the trip to Old Trafford.