The 16:30 BST kick-off provides ample opportunity for Erik ten Hag's team to get back to winning ways, after draws against Crystal Palace and FC Twente in the Premier League and Europa League, respectively.
Ahead of the match, former Reds Danny Simpson and Ben Thornley have been playing our United Predictions game, where you can select Erik's starting XI, the scoreline, who you think will find the net first and your Man of the Match - with the chance of winning great prizes.
Both Danny and Ben are tipping summer signing Manuel Ugarte to make his first-ever Premier League start against Ange Postecoglou's side on Sunday.