After an equal first half in which Kevin de Bruyne's two goals sandwiched Jadon Sancho's brilliant curler, Manchester City dominated after the break and scored twice more.
Maguire admits the result is "disappointing" and says the squad are "devastated" by the defeat, but insists attention must turn to several important upcoming games.
Here's what the skipper had to say...
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"We know it’s an important end to the season that we’ve got. It’s a run of games where we know that we’ve got to go on a run, we’ve got to go and pick up win after win after win and we’re more than capable of doing it but we’ve got to show it on the pitch, we’ve got to show it every game that we go into, take each game as it comes, a big game against Tottenham next.