Paulo Fonseca’s side, who were beaten 4-2 by fellow top-four challengers Strasbourg last weekend, went behind 47 seconds into what was billed as another key clash in the race for Europe.
Lille travelled to the match at the Groupama Stadium - where we will play on Thursday night - two points ahead of Les Gones and Bafode Diakite’s early header threatened to stretch that advantage further.
Star attacker Rayan Cherki was named on the bench but had to be introduced in the seventh minute, after Ernest Nuamah suffered a knee injury.
Diakite flashed another header narrowly wide, before good work by former Arsenal pair Ainsley Maitland-Niles and Alexandre Lacazette led to Thomas Meunier handling the ball in the box.