Read on for all the key details about our first knockout tie of 2020/21...
FOLLOW THE GAME
The action at Kenilworth Road will get under way at 20:15 BST, with live TV coverage in the UK available on Sky Sports. Club media will be all over it too of course, with frequent updates on ManUtd.com and in our Official App, while MUTV offers build-up from 19:10 BST followed by radio commentary and post-match analysis.
WHAT'S AT STAKE?
Up for grabs is a place among the last 16 teams in the competition, and unusually we already know the Reds or the Hatters will be away in the next phase.