Jadon Sancho, Marcus Rashford and Anthony Elanga have all performed in the position of late and, of course, there is the prospect that the wide men switch flanks regularly during the course of the game.
It's time to get your United Predictions in, in a bid to win some special prizes and climb the leaderboard, so we decided to focus on this slot in the side, ahead of a tough challenge with the Saints.
Ralph Hasenhuttl's side won 3-2 at Tottenham in midweek so will be in great spirits for the trip north. However, will Tino Livramento or Romain Perraud, the chief right-back options for the visitors, be in for a difficult 90 minutes?