There is free entry for all spectators, with the gates opening an hour before the start, as the two sides compete for the right to meet Chelsea in the semi-finals, following their 1-0 victory over Millwall on Thursday.
Unfortunately, the game cannot be shown live on MUTV as the Football Association have taken up the rights for exclusive coverage. The FA are expected to confirm later today which platform will show the action.
Wigan won the EFL Youth Alliance, EFL Youth Alliance Cup and Lancashire FA Youth Cup last term but suffered a first defeat in any competition since September, against Barnsley last weekend.