The competitive fixture at the Singapore National Stadium allows the boss to start planning for the Premier League opener against Chelsea at Old Trafford next month.
David De Gea and Luke Shaw return after being forced to miss the win over Leeds United in midweek, while Axel Tuanzebe, who did not get off the bench in that 4-0 victory, is handed a start in the middle of defence, alongside Victor Lindelof.
Marcus Rashford is out to score for the third successive game on Tour 2019 and he is likely to play in a central role with Anthony Martial reverting to his more familiar left-sided slot.