The Reds are looking to get back to winning ways, following back-to-back defeats against Brighton & Hove Albion and Liverpool.
This is a great ground on which to do just that, as we’re unbeaten in our last 15 visits to the Saints’ home, a run which dates back to 2003.
Here’s what you need to know ahead of the game…
HOW CAN I WATCH THE GAME?
The south-coast clash is being broadcast live on TNT Sports in the UK, while you can watch build-up on MUTV, available via ManUtd.com and in the United App, from 11:25 BST.