The Reds travel to Portman Road, where we’ll play Ipswich Town in the Premier League at 16:30 GMT.
It’s 22 years since we faced the Tractor Boys in the top-flight, but there is a sense of familiarity as they are managed by former United coach Kieran McKenna and have Academy graduate Axel Tuanzebe on the playing staff.
The Suffolk club chalked off their first win of the campaign at Tottenham last time out and will be aiming for another scalp, in what will be a momentous occasion as a new United era begins.
Here’s what you need to know…
HOW TO WATCH AND FOLLOW
Tune in to MUTV from 15:25 GMT for our Match Day Live show, with former Reds Danny Simpson and Danny Webber providing the punditry.