On the back of a successful return to action on Wednesday night – a 2-0 win at home to Burnley in the Carabao Cup – Erik ten Hag’s side will be hoping to restart our league season in similar fashion, when the Nottinghamshire side come to town.
The game will be our first in the competition in just over six weeks, following the World Cup break, and our first meeting with Forest since 1999.
So, ahead of the match in M16, here is everything you need to know…
The game is a 20:00 GMT kick-off at Old Trafford and will be broadcast live in the UK on Amazon Prime Video, while you will also be able to follow the action as it unfolds in the United App, on ManUtd.