The Academy product has been in good form for Manchester United and, of course, scored our goal in Sunday's Emirates FA Cup defeat to Leicester City. Opta explained how his 22nd goal since the start of last season is the most by a teenager in any of the top-five European leagues.
His withdrawal due to injury leaves Diogo Dalot (Portugal) and Matej Kovar (Czech Republic) as United's representatives in the tournament. Dalot is, of course, on loan at AC Milan, while Kovar has returned from a spell with Swindon Town.
England coach Aidy Boothroyd has called Norwich City's Todd Cantwell into his 23-man squad as a replacement.