United and Tottenham Hotspur have played against each other on 191 occasions, with our first meeting – a 1-1 draw in the FA Cup at Spurs’ old ground Asplins Farm – taking place in January 1899.
The Reds have recorded 90 wins against the north Londoners in all competitions, and we've delved into the archives to take a look at five of the most memorable...
United 4-1 Spurs, UEFA Cup Winners’ Cup second round, 10 December 1963
Bill Nicholson’s Spurs had become the first English team to win a European trophy the previous season, demolishing Atletico Madrid to claim the Cup Winners’ Cup.