It was already known that the Reds' opening match of the new league campaign - at home to Fulham - would be played on Friday night, 16 August, and be shown live on Sky Sports.
The broadcasters have now completed their picks for the first two months of the season, enabling clubs and their fans to plan ahead in more detail.
United's second game, away to Brighton & Hove Albion, will also now be moved from its provisional Saturday 15:00 BST slot. Remaining on the original date of 24 August, it will now kick off earlier at 12:30 BST and will be screened live on TNT Sports.