The game against Newcastle United at Leigh Sports Village, which kicks off at 19:00 GMT and is being shown live on MUTV, will be the first match action the pair have experienced this season after undergoing knee operations in the summer.
“Eric and Tim are going to play in the Reserves tonight,” revealed Ole Gunnar Solskjaer in an exclusive interview, prior to his Friday press conference.
“It's positive for them and they've been waiting for a long time, training for a while now, and it'll be good to see them in a proper kit.”
Bailly picked up a knee problem during the Tour 2019 friendly win over Tottenham Hotspur in Shanghai, after missing the end of the 2018/19 season with a similar issue.