Erik ten Hag's men will be facing La Liga side Real Betis in our second summer match on US soil, following last weekend's showdown with Premier League rivals Arsenal at SoFi Stadium.
Kick-off at the Snapdragon Stadium, on the campus of San Diego State University, is scheduled for 19:00 local time on Wednesday evening (03:00 UK time on Thursday morning) but before the match action begins, fans will be able to attend an event celebrating their loyalty and love for United.
A special Fanzone will be open outside the stadium, on the East Lawn, from 15:00 to 18:00 local time, and entry is free.