The game is to be staged on Tuesday 16 January, kicking off at 19:00 GMT.
MUTV coverage has still to be confirmed and details will follow in due course.
Supporters wishing to attend the game can buy tickets here.
Adam Lawrence's side have a 100 per cent record in the Under-18 Premier League North this term, and are relishing the opportunity to continue in this prestigious competition, one we won for the 11th time, in 2022, by beating Nottingham Forest in the final at Old Trafford.