The Brazilian replaced Marcus Rashford on 73 minutes but his night was cut short before the end, when he pulled up in pain.
After receiving treatment, he tried to play on but was soon signalling to the bench and ended up being taken off on a stretcher, with former team-mate Sofyan Amrabat keen to show his compassion and concern.
Ten Hag echoed that sentiment in his post-match interview in Istanbul with MUTV.
The boss said it was too early to gauge the extent of the problem for the wide man, who was seen leaving the stadium in a protective boot.