The Reds are unbeaten in the competition but, after three draws, are under pressure to move up the table and push for a top-eight spot and automatic place in the round of 16 next year.
Greek champions PAOK are 30th in the 36-team standings, with their only point coming from a 2-2 draw against another of our future opponents in Viktoria Plzen.
However, their domestic form has still been good, as they sit only a point behind leaders, and Salonika rivals, Aris.
United welcome Bruno Fernandes back from suspension, after he missed the 1-1 draw away to Fenerbahce, on the back of his red card in the game at FC Porto.