Alex Telles, who came on for Shaw in the first leg, is the natural replacement for Luke at left-back, while we await an update on Eric Bailly after his late return from international duty with Ivory Coast following a positive test for COVID-19. Axel Tuanzebe is a strong candidate to partner Victor Lindelof at the heart of the defence.
There are numerous options in midfield to replace McTominay as the Reds look to book a semi-final meeting with Roma or Ajax, following the Serie A side's 2-1 triumph in the first leg in Amsterdam.