The Reds were beaten 2-0 by West Ham United at the London Stadium on Saturday, as second-half strikes from Jarrod Bowen and Mohammed Kudus ensured victory for the Hammers.
Having dominated most of the play in east London, United left the capital ultimately empty-handed and will be looking for a response against Unai Emery's side on Tuesday.
Willy Kambwala came in for his first-team debut, while Diogo Dalot missed out given his recent red card against Liverpool at Anfield.
Raphael Varane fell ill ahead of our clash against David Moyes's side, and Erik ten Hag could provide an update on the centre-back in his pre-Villa press conference, which you will be able to see across our platforms from 22:30 GMT on Christmas Day.