The Spaniard was named in the starting XI that kicked-off against Brighton and Hove Albion at the Amex Stadium on Saturday tea-time. By lining up against the Seagulls, he made his 486th appearance for United, moving him into 11th place outright.
It means De Gea also now has one more appearance than our three-time FA Cup-winning Scottish full-back Arthur Albiston.
David remains second to Alex Stepney in terms of goalkeepers with the most appearances with Stepney on 539.
He is also only 24 games away from breaking into the overall top 10, with forward Joe Spence currently occupying that spot.