Altay Bayindir comes in for Andre Onana in goal, while Leny Yoro and Victor Lindelof replace Matthijs de Ligt and Harry Maguire at the back. De Ligt has not been included in the matchday squad due to illness.
Our further two changes across the starting XI see Christan Eriksen and Antony swap in for Mason Mount, who is injured, and Amad.
The Reds are bidding to make it into the last four of this season's Carabao Cup, but there is a tricky test against Ange Postecoglou's side to navigate through first.
Spirits are high after our most recent win, a 2-1 derby success over Manchester City in the Premier League on Sunday.