Cristiano Ronaldo is among those who aren’t featuring against Steve Gerrard’s side as we start our campaign in the famous competition.
Ronaldo misses out alongside Phil Jones, who performed well in the 1-0 Wolves defeat after almost two years out.
Jones’ place is taken by the returning Victor Lindelof. The Swedish international has been absent due to injury and then COVID-19 since the win at Norwich on 11 December. He will partner Raphael Varane.
Bruno Fernandes is back in the starting line-up and captains United. Marcus Rashford replaces Ronaldo up front in the Reds attack.
Fred is in for Nemanja Matic in midfield and Diogo Dalot replaces Aaron Wan-Bissaka at right back.