Jose Mourinho has made seven changes to his starting line-up to face FC Rostov (kick-off 18:00 GMT) in the Reds' first leg of their last-16 Europa League tie.
United overcame French outfit Saint-Etienne in the round of 32 and, after a disappointing draw against AFC Bournemouth on Saturday in the Premier League, Mourinho’s side are looking to take control of the Europa League tie.
Mourinho told reporters in his pre-match press conference that Zlatan Ibrahimovic would start following news of his three-match domestic ban. The boss also welcomes back Armenian attacking midfielder Henrikh Mkhitaryan as he returns following an injury suffered in the 1-0 away win over Saint Etienne.