Ole Gunnar Solskjaer's Reds welcome Frank Lampard's Blues to the Theatre of Dreams for the final match of the opening weekend, which kicks off at 16:30 BST.
The Reds drew 1-1 with the Blues in our penultimate home game last season, but there's been plenty of change at both clubs since that April encounter.
Here’s everything you need to know ahead of the big game…
HOW CAN I FOLLOW THE GAME?
MUTV subscribers will be able to watch live dedicated build-up to the game in the ‘Match Day’ show from 15:00 BST on Sunday, followed by live radio commentary.